It is the smallest and most central neighborhood of Venice. The first inhabitants settled in this neighbourhood of Venice, and from there it grew into a merchant neighbourhood in the 11th century. It became the commercial centre of Venice. In San Polo many important historical events occurred. The famous Rialto Bridge that crosses the Grand Canal is in this neighbourhood. San Polo is lively and bustling with a market environment, with many stalls and plenty of bars, it's in its maze of alleyways that you'll discover the most humble Venice.